diff --git a/ansible/roles/nova-cell/templates/nova.conf.d/libvirt.conf.j2 b/ansible/roles/nova-cell/templates/nova.conf.d/libvirt.conf.j2
index 10dda3fa4e..69d8f9363b 100644
--- a/ansible/roles/nova-cell/templates/nova.conf.d/libvirt.conf.j2
+++ b/ansible/roles/nova-cell/templates/nova.conf.d/libvirt.conf.j2
@@ -24,3 +24,6 @@ virt_type = {{ nova_compute_virt_type }}
 {% if nova_libvirt_cpu_mode %}
 cpu_mode = {{ nova_libvirt_cpu_mode }}
 {% endif %}
+{% if enable_multipathd | bool %}
+volume_use_multipath = True
+{% endif %}
diff --git a/releasenotes/notes/nova-libvirt-multipath-iscsi-eb961e44e6fec9ff.yaml b/releasenotes/notes/nova-libvirt-multipath-iscsi-eb961e44e6fec9ff.yaml
new file mode 100644
index 0000000000..bf28a2d1f2
--- /dev/null
+++ b/releasenotes/notes/nova-libvirt-multipath-iscsi-eb961e44e6fec9ff.yaml
@@ -0,0 +1,4 @@
+---
+upgrade:
+  - |
+    Enabling multipathd will now configure Nova to use it.