diff --git a/.zuul.yaml b/.zuul.yaml
index 35eecfd..a60d493 100644
--- a/.zuul.yaml
+++ b/.zuul.yaml
@@ -1,10 +1,8 @@
 - project:
     templates:
       - check-requirements
-      - lib-forward-testing
       - lib-forward-testing-python3
       - openstack-lower-constraints-jobs
-      - openstack-python-jobs
       - openstack-python3-ussuri-jobs
       - periodic-stable-jobs
       - publish-openstack-docs-pti
diff --git a/doc/requirements.txt b/doc/requirements.txt
index 9b0d49e..81dfe9d 100644
--- a/doc/requirements.txt
+++ b/doc/requirements.txt
@@ -3,6 +3,5 @@
 # process, which may cause wedges in the gate later.
 # These are needed for docs generation
 openstackdocstheme>=1.18.1 # Apache-2.0
-sphinx>=1.8.0,<2.0.0;python_version=='2.7' # BSD
-sphinx>=1.8.0,!=2.1.0;python_version>='3.4' # BSD
+sphinx>=1.8.0,!=2.1.0 # BSD
 reno>=2.5.0 # Apache-2.0
diff --git a/lower-constraints.txt b/lower-constraints.txt
index a8331a3..f0d211c 100644
--- a/lower-constraints.txt
+++ b/lower-constraints.txt
@@ -15,7 +15,6 @@ keystoneauth1==3.4.0
 linecache2==1.0.0
 mccabe==0.2.1
 mock==2.0.0
-monotonic==0.6
 mox3==0.20.0
 msgpack==0.5.2
 netaddr==0.7.18
diff --git a/releasenotes/notes/drop-python27-support-185668eec068ffa5.yaml b/releasenotes/notes/drop-python27-support-185668eec068ffa5.yaml
new file mode 100644
index 0000000..c5195c0
--- /dev/null
+++ b/releasenotes/notes/drop-python27-support-185668eec068ffa5.yaml
@@ -0,0 +1,5 @@
+---
+upgrade:
+  - |
+    Support for Python 2.7 has been dropped. The latest version of Python now
+    supported is Python 3.6.
diff --git a/setup.cfg b/setup.cfg
index 578c578..af14e83 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -6,6 +6,7 @@ description-file =
 author = OpenStack
 author-email = openstack-discuss@lists.openstack.org
 home-page = https://docs.openstack.org/oslo.serialization/latest/
+python-requires = >=3.6
 classifier =
     Environment :: OpenStack
     Intended Audience :: Information Technology
@@ -13,11 +14,11 @@ classifier =
     License :: OSI Approved :: Apache Software License
     Operating System :: POSIX :: Linux
     Programming Language :: Python
-    Programming Language :: Python :: 2
-    Programming Language :: Python :: 2.7
     Programming Language :: Python :: 3
     Programming Language :: Python :: 3.6
     Programming Language :: Python :: 3.7
+    Programming Language :: Python :: 3 :: Only
+    Programming Language :: Python :: Implementation :: CPython
 
 [files]
 packages =
@@ -36,6 +37,3 @@ input_file = oslo.serialization/locale/oslo.serialization.pot
 keywords = _ gettext ngettext l_ lazy_gettext
 mapping_file = babel.cfg
 output_file = oslo.serialization/locale/oslo.serialization.pot
-
-[bdist_wheel]
-universal = 1
diff --git a/setup.py b/setup.py
index 566d844..f63cc23 100644
--- a/setup.py
+++ b/setup.py
@@ -16,14 +16,6 @@
 # THIS FILE IS MANAGED BY THE GLOBAL REQUIREMENTS REPO - DO NOT EDIT
 import setuptools
 
-# In python < 2.7.4, a lazy loading of package `pbr` will break
-# setuptools if some other modules registered functions in `atexit`.
-# solution from: http://bugs.python.org/issue15881#msg170215
-try:
-    import multiprocessing  # noqa
-except ImportError:
-    pass
-
 setuptools.setup(
     setup_requires=['pbr>=2.0.0'],
     pbr=True)
diff --git a/test-requirements.txt b/test-requirements.txt
index 6882afd..232fb68 100644
--- a/test-requirements.txt
+++ b/test-requirements.txt
@@ -2,7 +2,6 @@
 # of appearance. Changing the order has an impact on the overall integration
 # process, which may cause wedges in the gate later.
 hacking>=1.1.0,<1.2.0 # Apache-2.0
-ipaddress>=1.0.17;python_version<'3.3' # PSF
 mock>=2.0.0 # BSD
 netaddr>=0.7.18 # BSD
 stestr>=2.0.0 # Apache-2.0
diff --git a/tox.ini b/tox.ini
index 8b2809b..e8a2e76 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,8 +1,8 @@
 [tox]
 minversion = 3.1
-envlist = py27,py37,pep8
+envlist = py37,pep8
 basepython = python3
-ignore_basepython_conflict = True
+ignore_basepython_conflict = true
 
 [testenv]
 deps =